Saturday , 25 November 2017

Medieval Medicine More Successful Against Superbugs Than Antibiotics

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It may sound unbelievable, but a thousand-year-old Anglo-Saxon medicine for ocular infection could be crucial in the eradicating of modern superbugs. The medicine, based on garlic, is still in the testing stage but proved to be an incredibly effective.

Recipe for a balm anti ocular infections from the 10th century was discovered in a British Library in the book Bald’s Leechbook, which is considered as one of the earliest medical textbooks.

Christina Li, an expert on Anglo-Saxon society of the University of Nottingham, translated the ancient texts.

“We chose this recipe because it contains ingredients such as garlic, which is currently being tested as a replacement for antibiotics,” said Kristina Li.

Her colleagues microbiologists from the University took care to make the medicine by using exact instructions. Medicine asking for onion and garlic, wine and ox bile.

“We kept thoroughly on the recipe. In ancient textbook are precisely specified instructions and referring ingredients and the whole mixture after mixing has to be left for nine days before it is filtered through gauze, “says Freya Harrison, who led the work on a cure.

They immediately tested the resulting compound against the cultured colony culture superbug MRSA (Methicillin-resistant Staphylococcus aureus), type of staphylococci that does not respond to common antibiotics.

Although they have not claimed excessive hopes, the results were very surprised. “We came to the conclusion that balm for the eyes from 10th century is an extremely potent as anti-staphylococcal antibiotic,” said Harrison.

According to her, a mature bacterial colony of several billion cells, which has quite nice developed, was reduce to just a few thousand of the remaining cells, which is extremely deadly.

British scientists have asked their colleagues in the US to test the recipe on living organisms, which had the result that the new medicine was more effective than conventional antibiotic treatment.

The most important thing is that they managed to create new volumes, which also had the same results. Another important fact is that the medicine retains strength even after a long time stored in the fridge.

Now they have documented research that medicine kills up to 90 percent of MRSA bacteria in mice.

Harrison notes that they have not completely sure yet how medicine works. They find that it probably comes that several active components work together in attacking the bacteria, making it difficult for bacteria defense.

They also believe that by leaving the medicine in alcohol prior to using creates a new molecule that contributes to the fight against bacteria.

“Although we can not say with great certainty yet that the medicine because works in the laboratory will work as an antibiotic also, but there is great potential for something like that,” Harrison said.

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